Powered by mannitol—SPI Pharma’s most versatile excipient
When it comes to chewable tablets, mannitol has been the preferred excipient due to its favorable mouthfeel and versatility. Now, we’ve made it even easier to blend and compress actives that are difficult to tablet—and expand your product lines to include lozenge and sublingual forms to meet specific patient needs. SPI Pharma’s spray-dried mannitol product, Mannogem® EZ, is an excellent option for orally disintegrating tablets when raw material cost is a primary constraint.
Mannitol has always been a useful excipient for tablets because it protects water-sensitive actives from degradation and doesn’t react with the active ingredient. Mannogem EZ is even more functional. It has a very narrow particle size distribution, excellent mouthfeel, superior flow properties, and a solid compression profile, providing a versatile option for multiple pharmaceutical applications including lozenges and sublingual dosage forms. Its low solubility and rapid disintegration characteristics also make it a good choice for ODT formulations.
Mannogem EZ spray-dried mannitol offers you the following benefits:
- Highly compactible
- Smooth mouthfeel
- Sweet taste (50% as sweet as sucrose)
- Chemically inert
- Narrow particle size distribution helps reduce segregation
- Rapid disintegration property benefits quick-dissolve applications
- Meets USP and/or EP compendia requirements
- Produced under cGMP conditions
Find out why SPI Pharma has been a leading manufacturer of mannitol-based products for the pharmaceutical industry for more than 75 years by exploring our full line of Mannogem products today.