An innovative platform for a patient-friendly dosage form
Orally disintegrating technology represents an advanced development—and growing trend—in pharmaceutical dosage forms, offering considerable advantages for life cycle management, development timelines, patient convenience and compliance, and market share.
SPI Pharma's innovative oral disintegrating technology platform, Pharmaburst® 500, has been successfully used in more than 60 marketed products worldwide. Global pharmaceutical manufacturers choose Pharmaburst ODT technology to formulate their drugs as oral disintegrating tablets because of its many benefits, including:
- Optimal compactibility with rapid disintegration, for ODT tablets that are durable enough to withstand packaging and handling, yet meet the requirements for rapid disintegration (less than 30 seconds)
- High component solubility, enabling the formulation of a fast-disintegrating ODT tablet even at high dosage levels (up to 500 mg)
- Superior organoleptic properties, helping to ensure that each orally disintegrating tablet is palatable and provides a pleasant sensory experience
- Cost-effectiveness and accelerated speed to market for product line extensions and entry into new markets and patient populations
Pharmaburst ODT technology is a ready-to-use system, scientifically engineered to manufacture robust, rapidly disintegrating tablets using standard tableting equipment. Simply blend your dry active ingredient, flavor, and color with Pharmaburst to achieve tablets with exceptional organoleptic properties.
To create a robust tablet that can withstand packaging and handling, our orally disintegrating tablet technology platform can be integrated with your standard direct compression process. Our ODT technology is optimized to deliver a robust, rapidly disintegrating tablet with superior organoleptic properties, using only your current tableting equipment.
Creating unique product formulations
Pharmaburst ODT technology can be combined with our proprietary taste-masking solutions to create customized tablets with benefits such as:
- Acceptability of orally administered drugs that have a bitter taste
- Increased compliance among populations who may reject unpalatable tablets, such as pediatric or psychiatric patients
- Better therapeutic efficacy and bioavailability of certain drugs
- Improved stability in some drugs
- Improved organoleptic characteristics
A fully balanced and optimized system
Not all ODT technologies are created equal! Pharmaburst ODT technology can enhance compliance by providing patients with a convenient, easy-to-swallow product with a pleasant taste—as well as delivering benefits to you such as cost savings, simplified manufacturing, and our proven expertise and track record of success in the global ODT market.
Partner with SPI Pharma for the highest-quality orally disintegrating technology and formulation solutions—along with expert service, support, and additional products to streamline your formulation process and accelerate your time to market.